Recombinant Fasciola hepatica Fatty Acid Binding Protein as a Novel Anti-Inflammatory Biotherapeutic Drug in an Acute Gram-Negative Nonhuman Primate Sepsis Model Academic Article uri icon

abstract

  • Sepsis caused by Gram-negative bacteria affects 1.7 million adults annually in the United States and is one of the most important causes of death at intensive care units. Although the effective use of antibiotics has resulted in improved prognosis of sepsis, the pathological and deathly effects have been attributed to the persistent inflammatory cascade.

authors

  • Rosado-Franco, Jose J.
  • Armina-Rodriguez, Albersy
  • Marzan-Rivera, Nicole
  • Burgos, Armando G.
  • Spiliopoulos, Natalie
  • Dorta-Estremera, Stephanie M.
  • Mendez, Loyda B.
  • Espino, Ana M.

publication date

  • 2021

volume

  • 9

issue

  • 3